Peer-reviewed journal publications 

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R Gerver & AE Herr. "Microfluidic Western blotting of low molecular mass proteins." Analytical Chemistry, 2014, accepted.

Y Pan, TA Duncombe, C Kellenberger, MC Hammond & AE Herr. "High-throughput electrophoretic mobility shift assays for quantitative analysis of molecular binding reactions." Analytical Chemisry, 2014, accepted.

C-C Kang, J-M Lin, Z Xu, S Kumar & AE Herr. "Single-cell western blotting after whole-cell imaging to assess cancer chemotherapeutic response." Analytical Chemisry, 2014, accepted.

M Chung*, D Kim* & AE Herr. "Polymer sieving matrices in microanalytical electrophoresis." Analyst, 2014, accepted.*Equal contributors (Invited Review)

AJ Hughes*, DM Spelke*, Z Xu, C-C Kang, DV Schaffer, & AE Herr. "Single-cell western blotting." Nature Methods, 2014, 11(7):749-55.*Equal contributors

AM Tentori & AE Herr. "Performance implications of chemical mobilization after microchannel isoelectric focusing." Electrophoresis, 2014, 35(10):1453-60.

MA Kapil & AE Herr. "Binding kinetic rates measured via electrophoretic band crossing in a pseudo-homogeneous format." Analytical Chemistry, 2014, 4;86(5):2601-9.

Y Pan, K Karns, & AE Herr. "Microfluidic electrophoretic mobility shift assays for quantitative biochemical analysis." Electrophoresis, 2014, accepted.(Invited Review)

MK Araz, AA Apori, C Salisbury, & AE Herr. "Microfluidic barcode assay for antibody-based confirmatory diagnostics." Lab on a Chip, 2013, 13(19):3910-20.

M Chung, D Kim, & AE Herr. "Microchamber Western blotting using poly-L-lysine conjugated polyacrylamide gel for blotting of SDS coated proteins." Analytical Chemistry, 2013, 85(16):7753-61.

D Kim & AE Herr. "Protein immobilization techniques for microfluidic assays." Biomicrofluidics, 2013, 7(4):41501.

AE Herr. "Disruptive by Design: A perspective on engineering in analytical chemistry." Analytical Chemistry, 2013, 85(16):7622-8.

MK Araz, AM Tentori, & AE Herr. "Microfluidic multiplexing in bioanalyses." JALA, 2013, 18(5):350-66. (Invited Review)

AM Tentori, AJ Hughes, & AE Herr. "Microchamber Integration unifies distinct separation modes for Two-Dimensional Electrophoresis." Analytical Chemistry, 2013, 85(9):4538-4545.

TA Duncombe & AE Herr. "Photopatterned free-standing polyacrylamide gels for microfluidic protein electrophoresis." Lab Chip, 2013, 13(11):2115-23.

K Karns, JM Vogan, Q Qin, S Hickey, MC Hammond & AE Herr. "Microfluidic Screening of Electrophoretic Mobility Shifts Elucidates Riboswitch Binding Function." Journal of the American Chemical Society (JACS), 2013, 135(8):3136-43.

AA Apori, M Brozynski, I El-Sayed, & AE Herr. "Microfluidic validation of diagnostic protein markers for spontaneous cerebrospinal fluid rhinorrhea." Journal of Proteome Research, 2013, 12(3):1254-65.

SQ Tia, K Brown, D Chen & AE Herr. "Protein post-translational modification analyses using immunoprobed isoelectric focusing."Analytical Chemistry, 2013, 85(5):2882-90.

C Hou & AE Herr. "Microfluidic integration of Western blotting is enabled by electrotransfer-assisted sodium dodecyl sulphate dilution." Analyst, 2013, 138(1):158-63.

AJ Hughes & AE Herr. "Microfluidic Western blotting." Proceedings of the National Academy of Sciences USA, 2012, 109(52):21450-5.

TA Duncombe & AE Herr. "Polyacrylamide gel moving boundary electrophoresis enables low-power protein analysis in a compact microdevice."Analytical Chemistry, 2012, 84(20):8740-7.

AJ Hughes*, AM Tentori*, & AE Herr. "Bistable isoelectric point photoswitching in green fluorescent proteins observed by dynamic immunoprobed isoelectric focusing." Journal of the American Chemical Society (JACS), 2012, 134(42):17582-91. *Equal contributors

AK Denisin*, K Karns*, & AE Herr. "Post-collection processing of Schirmer Strip-collected human tear fluid impacts protein content." Analyst, 2012, 137(21):5088-96. *Equal contributors

AJ Hughes, RKC Lin, DM Peehl, & AE Herr. "Microfluidic integration for automated targeted proteomic assays." Proceedings of the National Academy of Sciences USA, 2012, 109(16):5972-7.

D Kim, K Karns, S Tia, M He, & AE Herr."Electrostatic protein immobilization using charged polyacrylamide gels and cationic detergent microfluidic Western Blotting." Anal Chem, 2012, 84(5), pp 2533-40.

M He, J Novak, B Julian & AE Herr. "Membrane assisted on-line renaturation for automated microfluidic lectin blotting." JACS, 2011, 133(49):19610-3.

K Karns & AE Herr. "Human tear protein analysis enabled by an alkaline microfluidic homogeneous immunoassay." Analytical Chemistry, 2011, 83(21):8115-22.

X Chen, M Kapil, AJ Hughes & AE Herr. "A single-microchannel, multi-step assay reports protein size and immunoaffinity." Analytical Chemistry, 2011, 83(17):6573-9.

SQ Tia, M He, D Kim & AE Herr. "Multi-analyte on-chip native Western blotting." Analytical Chemistry, 2011, 83(9):3581-8.

AM Tentori & AE Herr. "Photopatterned materials in bioanalytical microfluidic technology." J. Micromech. Microeng, 2011, 21(5):54001.

A Apori & AE Herr. "Homogeneous immunosubtraction integrated with sample preparation is enabled by a microfluidic format." Analytical Chemistry, 2011, 83(7):2691-8.

JS Kinney, T Morelli, T Braun, CA Ramseier, AE Herr, JV Sugai, CE Shelburne, LA RAyburn, AK Singh, WV Giannobile. "Saliva/pathogen biomarker signatures and periodontal disease progression." Journal of Dental Research, 2011, 90(6):752-8.

M He & AE Herr. "Automated microfluidic protein immunoblotting." Nature Protocols, 2010, 5, 1844-56.[ pdf SI ]

AJ Hughes & AE Herr. "Quantitative enzyme activity determination with zeptomole sensitivity by microfluidic hradient-hel zymography." Analytical Chemistry, 2010, 82, 3803-11.[ pdf SI ]

C Hou & AE Herr. "Ultra-short separation length homogeneous electrophoretic immunoassays using on-chip discontinuous Polyacrylamide gels." Analytical Chemistry, 2010, 82, 3343-51.[ pdf ]

M He & AE Herr. "Polyacrylamide gel photopatterning enables automated protein immunoblotting in a two-dimensional microdevice." Journal of the American Chemical Society, 2010, 132, 2512-2513.[ pdf SI ]

M He & AE Herr. "Microfluidic polyacrylamide gel electrophoresis with in-situ immunoblotting for native protein analysis." Analytical Chemistry, 2009, 81, 8177-84.[ pdf ]

N Srivastava, JS Brennan, RF Renzi, M Wu, SS Branda, AK Singh, & AE Herr. "Fully-integrated microfluidic platform enables automated phosphoprofiling of macrophage response." Analytical Chemistry, 2009, 81, 3261-3269.[ pdf ]

S Tia & AE Herr. "On-chip technologies for multi-dimensional separations." Lab Chip, 2009, 9, 2524 - 2536.[ pdf ]

CA Ramseier, JS Kinney, AE Herr, T Braun, JV Sugai, CA Shelburne, LA Rayburn, HM Tran, AK Singh, WV Giannobile. "Identification of pathogen and host-response markers correlated with periodontal disease." J Periodontol, 2009, 80(3), 436-46.[ pdf ]

C Hou & AE Herr. "Clinically-relevant advances in on-chip affinity-based electrophoresis and electrochromatography." Electrophoresis, 2008, 29, 3306-3319. [ pdf ] (Invited Review)

CT Lo¹, DJ Throckmorton¹, AK Singh & AE Herr. "Photopolymerized diffusion-defined polyacrylamide gradient gels for on-chip protein sizing." Lab Chip, 2008, 8, 1273-1279. ¹equal contributors [ pdf ][ RSC Chemical Biology ] Selected as a 2008 Hot Article

AE Herr, AV Hatch, DJ Throckmorton, HM Tran, JS Brennan, WV Giannobile, AK Singh. "Microfluidic immunoassays as rapid saliva-based clinical diagnostics." Proc Natl Acad Sci USA, 2007, 104(13), 5268-5273. [ pdf ][ NIH 'Research Matters' ][ NIH press release ]

AE Herr, AV Hatch, WV Giannobile, DJ Throckmorton, HM Tran, JS Brennan, AK Singh. "Integrated microfluidic platform for oral diagnostics." Ann NY Acad Sci, 'Oral Based Diagnostics, Part VI: Horizons in Oral Diagnostics', 2007, 1098, 362-374.

AV Hatch, AE Herr, DJ Throckmorton, JS Brennan, and AK Singh. "Integrated preconcentration SDS-PAGE of proteins in microchips using photopatterned cross-linked polyacrylamide gels." Analytical Chemistry, 2006, 78(14), 4976 - 4984. [ pdf ]

VC Rucker, KL Havenstrite, BA Simmons, SM Sickafoose, AE Herr, R Shediac. "Functional antibody immobilization on 3-dimensional polymeric surfaces generated by reactive ion etching." Langmuir, 2005, 21(17), 7621-7625. [ pdf ]

VC Rucker, KL Havenstrite, AE Herr. "Antibody microarrays for native toxin detection." Anal Biochem, 2005, 339(2), 262-270.

AE Herr, DJ Throckmorton, AA Davenport, AK Singh. "On-chip native gel electrophoresis-based immunoassays for tetanus antibody and toxin." Analytical Chemistry, 2005, 77(2), 585-590. [ pdf ]

AE Herr & AK Singh. "Photopolymerized cross-linked polyacrylamide gels for on-chip protein sizing." Analytical Chemistry, 2004, 76(16), 4727-33. [ pdf ]

AE Herr, JI Molho, KA Drouvalakis, JC Mikkelsen, PJ Utz, JG Santiago, TW Kenny, "On-Chip coupling of isoelectric focusing and free solution electrophoresis for Multi-Dimensional Separations," Anal Chem, 2003, 75(5), 1180-1187. [ pdf ]

F Raisi, P Belgrader, DA Borkholder, AE Herr, GJ Kintz, F Pourhamadi, MT Taylor, MA Northrup, "Microchip isoelectric focusing using a miniature scanning detection system", Electrophoresis, 2001, 22(11), 2291-2295. [ pdf ]

JI Molho, AE Herr, BP Mosier, JG Santiago, TW Kenny, RA Brennen, GB Gordon, B Mohammadi. "Optimization of turn geometries for microchip electrophoresis," Anal Chem, 2001, 73(6),1350-1360. [ pdf ]

AE Herr, JI Molho, JG Santiago, MG Mungal, TW Kenny, MG Garguilo. "Electroosmotic capillary flow with nonuniform Zeta potential." Analytical Chemistry, 2000, 72(5), 1053-1057. [ pdf ]

 

Conferences, book chapters & invited talks 

please see Prof. Herr's [ CV ]