A major focus of our lab is engineering innovation for analysis of complex biological systems — as is required to address questions important to both fundamental biological systems and applied clinical research. We employ a combination of approaches drawn from bioengineering, chemical engineering, mechanical engineering, and electrical engineering with strong foundations in biology, materials science, and analytical chemistry. In essence, we strive to advance the “mathematization” of biology & medicine.
We are part of the UC Berkeley Department of Bioengineering and the UC Berkeley/UCSF Graduate Group in Bioengineering. A primary focus of our research is in tools to push the frontier of single-cell biology. To accomplish this, we design and create instrumentation that exploits scale-dependent physics and chemistry. Our work accelerates development of bioanalytical methods, streamlines sample preparation strategies, improves biomarker validation studies, and advances clinical diagnostics.
Affiliations: QB3: The California Institute of Quantitative Biosciences, The Chan Zuckerberg Biohub, The Berkeley Stem Cell Center, Jacobs Institute of Design Innovation, and The Lawrence Berkeley National Laboratory.
Graduate student researchers join us from a variety of UC Berkeley & UCSF Graduate Programs: Bioengineering, Chemical Biology, and Applied Science & Technology, as well as various engineering & chemistry programs.
News
- Our preprint “Single-cell organelle extraction with cellular indexing” by co-authors Trinh, Ana, Anna, and lab alumna Ali is available on bioRxiv and under peer review.
- Congrats to new lab member X Sun, co-advised with Prof. Hayden Taylor (ME), who passed her Mechanical Engineering Qualifying Exam!
- Prof. Herr’s co-authored paper “How to build the virtual cell with artificial intelligence: Priorities and opportunities” is now published at Cell.
- Welcome to our lab’s new postdoctoral fellow working on joint-cell analysis (multi omics) and AI/ML, Dr. Xin Wang!
- Congratulations to Nazibul & Yang on our paper “Electromigration of Charged Analytes Through Immiscible Fluids in Multiphasic Electrophoresis” accepted at the journal Electrophoresis.
- Trinh wins Best Paper Award at MicroTAS 2024 for “scBlot-seq: A Multi-modal, same-cell assay for chromatin accessibility and protein immunoblotting”, with co-authors Anna, Amy, and alumna Ali Su.